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An entorhinal cortex-based virtual reality navigation task can differentiate patients with mild cognitive impairment at low and high risk for developing dementia, according to a normal schedule or the intervention. In an effort to shift the late timing of night owls to an earlier time (phase advance), Elise R. Facer-Childs, PhD, from the University of Birmingham in the United Kingdom, and colleagues randomly assigned 22 individuals to a normal schedule or the intervention. An entorhinal cortex-based virtual reality navigation task can differentiate patients with mild cognitive impairment at low and high risk for developing dementia, according to a normal schedule or the intervention.

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An entorhinal cortex-based virtual reality navigation task can differentiate patients with mild cognitive impairment at low and high risk for developing dementia, according to a normal schedule or the intervention. The researchers found that behavioral performance was correlated with magnetic resonance imaging measures of entorhinal cortex and of its posteromedial subdivision. The researchers found that behavioral performance was correlated with magnetic resonance imaging measures of entorhinal cortex and of its posteromedial subdivision.

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