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The dosage is determined by patient weight and can be administered orally or via gastrostomy tube. The most common adverse reactions reported with trofinetide were diarrhea and vomiting. The product, which received FDA approval in March 2023, was approved based on data from the randomized, double-blind, placebo-controlled phase 3 LAVENDER study (ClinicalTrials. Daybue is supplied as a strawberry-flavored oral solution containing 200 mg of trofinetide per mL.

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